B12 (Methylcobalamin) prices

FROM PEPTIDES CALCULATOR

About B12 Methylcobalamin

Source profile reviewed 2026-10-01 · Imported 2026-10-22. Read the full compound profile

Methylcobalamin is one of the two coenzyme forms of vitamin B12 in human cells, where it serves methionine synthase in the methylation cycle; the other, adenosylcobalamin, works inside mitochondria. It is sold as a prescription injectable in Japan and much of Asia (Eisai's Methycobal, 500 mcg per 1 mL ampoule) for peripheral neuropathy and B12-deficiency anemia, but there is no FDA-approved standalone methylcobalamin product in the United States, where cyanocobalamin and hydroxocobalamin are the approved injectable forms and methylcobalamin is prepared by 503A compounding pharmacies, usually at 1,000 to 5,000 mcg/mL. A Japanese phase 3 trial of 50 mg intramuscularly twice weekly slowed functional decline in early amyotrophic lateral sclerosis, and Eisai moved toward a Japanese approval on that basis. Research vendors sell it as a ready-to-use 20 mL liquid (one reseller lists the vendor version at 2,500 mcg/mL), and the legacy page for this product gave 1 mL once a week.

Formula

C63 H91 Co N13 O14 P

Molar mass

1,344.4 g/mol

CAS number

13422-55-4

Research evidence described in the source

Limitations noted in the source

• Individual claims and source links have not yet completed editorial verification.
• Evidence level, applicable study model, formulation, route and population remain unassigned.

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