MGF prices

FROM PEPTIDES CALCULATOR

About MGF

Source profile reviewed 2026-10-01 · Imported 2026-10-22. Read the full compound profile

MGF (mechano growth factor) is the name Geoffrey Goldspink's group gave to a splice variant of the IGF-1 gene (IGF-1Ec in humans, IGF-1Eb in rodents) that skeletal muscle switches on for a few days after mechanical loading or injury; the peptide sold under that name is a synthetic 24-residue fragment of the variant's C-terminal E domain. In cell culture and animal models this E-peptide has been reported to activate muscle satellite cells, protect neurons after brain ischemia and limit damage after experimental heart attack, but two pharmaceutical companies failed to reproduce any effect on muscle cells in 2014 and no pharmacokinetic study or human trial of the injected peptide has ever been published. MGF appears on the WADA prohibited list under growth factors (S2.3), the pegylated form PEG-MGF sat in the FDA's compounding Category 2 from 2023 until its nomination was withdrawn in April 2026, and a doping control laboratory found that a product marketed as full-length MGF did not match any known MGF-related molecule.

Formula

C121 H199 N41 O40

Molar mass

2,868.1 g/mol

Amino acids

24

Research evidence described in the source

Limitations noted in the source

• Individual claims and source links have not yet completed editorial verification.
• Evidence level, applicable study model, formulation, route and population remain unassigned.

Background is reproduced from Peptides Calculator with attribution. The source describes compound-level research. It does not evaluate the identity, quality or suitability of a listed supplier’s product or batch.