For laboratory research only. Not for human consumption.Our comparison method ↗
Studio-style Deals on Peptides product visual for P-21

Vial comparison

P-21 prices

Compare P-21 listings by strength, selection and supplier. Inspect the original source behind each price.

2suppliers represented
4source-linked listings
1strengths available

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DOCUMENTATION PASSPORTS

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Listed amounts and selections

  • 12 mg2 suppliers · Pack counts: 1, 10

Reported quantities in this family: 1, 10. Counts and units must be matched to the exact listing.

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Single-vial price overview

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Listed total prices before additional promotions or coupon estimates. Includes supplier captures and aggregator reports; capture dates do not confirm current vendor price or stock. Shipping and tax extra. Open the source before relying on a price.
StrengthSelectionLowest listed total pricePrice per mgSupplier countCompare
12 mg1 vial$119.00$9.922Compare

Suppliers with P-21 listings

2 profiles

Sources and comparison limits

4 listings from direct supplier captures. Capture and import dates record when data was obtained; they do not guarantee the supplier’s current price or stock.

Listings include out-of-stock and unconfirmed-stock records. Inclusion does not certify a supplier, a batch or a product. Read how matching and source dates work.

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FROM PEPTIDES CALCULATOR

About P21

Source profile reviewed 2026-10-01 · Imported 2026-10-22. Read the full compound profile

P21 (published as P021) is a small synthetic peptide built from a four-residue stretch of human ciliary neurotrophic factor (CNTF), with an acetyl group on the N-terminus and an adamantylated glycine amide on the C-terminus added to slow enzymatic breakdown and help it cross the blood-brain barrier. It was designed in Khalid Iqbal's laboratory at the New York State Institute for Basic Research and is reported to work by competing with leukemia inhibitory factor and raising BDNF expression, which in rodents increased hippocampal neurogenesis, lowered GSK3-beta activity and tau phosphorylation, and improved memory. Every published study is in mice, rats or cell culture, nearly all from the originating laboratory, and the one in vivo test run elsewhere (a CDKL5 deficiency model) did not reproduce the BDNF increase. No human trial has been registered, no regulator has approved it, and it is sold only as a research chemical in 5 mg vials.

Formula
C27 H42 N6 O8
Molar mass
578.7 g/mol
CAS number
1246751-68-7
Amino acids
5

Research evidence described in the source

Not graded

What is P21?

Understanding P21's role as a CNTF mimetic

Not graded

Research on P21

Development, mechanism of action, and therapeutic applications

Limitations noted in the source

  • Individual claims and source links have not yet completed editorial verification.
  • Evidence level, applicable study model, formulation, route and population remain unassigned.
Publications and references linked by the source

Background is reproduced from Peptides Calculator with attribution. The source describes compound-level research. It does not evaluate the identity, quality or suitability of a listed supplier’s product or batch.