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Atomik Labz
122 products · 249 listings
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Vial comparison
PE-22-28 prices
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2suppliers represented
4source-linked listings
1strengths available
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Listed amounts and selections
- 8 mg2 suppliers · Pack counts: 1, 10
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| Strength | Selection | Lowest listed total price | Price per mg | Supplier count | Compare |
|---|---|---|---|---|---|
| 8 mg | 1 vial | $60.00 | $7.50 | 2 | Compare |
Suppliers with PE-22-28 listings
2 profiles
Solution Peptides
153 products · 275 listings
Sources and comparison limits
4 listings from direct supplier captures. Capture and import dates record when data was obtained; they do not guarantee the supplier’s current price or stock.
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FROM PEPTIDES CALCULATOR
About PE-22-28
Source profile reviewed 2026-10-01 · Imported 2026-10-22. Read the full compound profile
PE-22-28 is a seven-amino-acid fragment (Gly-Val-Ser-Trp-Gly-Leu-Arg) of the propeptide released when the receptor sortilin matures, designed in 2017 by Jean Mazella, Marc Borsotto and colleagues at the CNRS Institute of Molecular and Cellular Pharmacology in Nice from the breakdown products of their earlier 17-residue peptide spadin. It blocks the TREK-1 background potassium channel with an IC50 of 0.12 nM, several hundred times more potently than spadin, and in mice it reduced depression-like behaviour, increased hippocampal neurogenesis within 4 days and kept working for roughly 23 hours after a single injection; the same group later reported that very low doses protected mice after experimental stroke while higher doses prevented post-stroke depression. All published work is in mice and cultured cells using intraperitoneal injection or oral gavage; there is no human study, no registered trial and no approval, and the intranasal spray favoured by the research-peptide community has never been tested in any species.
- Formula
- C35 H55 N11 O9
- Molar mass
- 773.9 g/mol
- CAS number
- 1801959-12-5
- Amino acids
- 7
Research evidence described in the source
Research on PE-22-28
Understanding TREK-1 and therapeutic applications
Limitations noted in the source
- Individual claims and source links have not yet completed editorial verification.
- Evidence level, applicable study model, formulation, route and population remain unassigned.
Publications and references linked by the source
Background is reproduced from Peptides Calculator with attribution. The source describes compound-level research. It does not evaluate the identity, quality or suitability of a listed supplier’s product or batch.