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Solution Peptides
153 products · 275 listings
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Pinealon Atomized Solution Kit prices
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FROM PEPTIDES CALCULATOR
About Pinealon
Source profile reviewed 2026-10-01 · Imported 2026-10-22. Read the full compound profile
Pinealon is the tripeptide Glu-Asp-Arg (also written EDR), one of the short synthetic bioregulators developed at the St. Petersburg Institute of Bioregulation and Gerontology under Vladimir Khavinson and assigned in that scheme to the pineal gland and brain. Its developers report that it limits reactive oxygen species and cell death in neurons under oxidative or low-oxygen stress, that it binds DNA and alters expression of genes such as CASP3, GAP43, SOD2 and APOE, and that it protects dendritic spines in Alzheimer models. The human record is thin: the one study that states a regimen gave 100 mcg twice daily by capsule for two weeks to Russian locomotive crews and reported better composite biological-age scores, with no control group, no randomisation and publication in Russian. No trial is registered, no regulator has approved it, and it is sold as Russian capsules of about 100 mcg and as 10 or 20 mg research vials, a format that does not appear anywhere in the human literature.
- Formula
- C15 H26 N6 O8
- Molar mass
- 418.4 g/mol
- CAS number
- 175175-23-2
- Amino acids
- 3
Research evidence described in the source
Prenatal hyperhomocysteinemia model
Rat-offspring research reported changes in oxidative stress and neuronal cell death.
Small uncontrolled reports
Published clinical observations lack proper randomization, blinding, and independent replication.
Single-network evidence base
Most work comes from the originating St Petersburg research group.
Limitations noted in the source
- No large randomized, placebo-controlled human trial establishes cognitive benefit.
- Combination and open-label designs prevent attribution of reported outcomes to Pinealon.
- A calculator preset is a recorded research convention, not a recommendation or evidence of clinical benefit.
- Identity, purity, sterility, and stability can vary substantially outside regulated manufacturing.
Publications and references linked by the source
- pubchem.ncbi.nlm.nih.gov/compound/10273502
- pubmed.ncbi.nlm.nih.gov/22708445/
- pubmed.ncbi.nlm.nih.gov/26390612/
- pubmed.ncbi.nlm.nih.gov/21978084/
- pmc.ncbi.nlm.nih.gov/articles/PMC3342713/
- pmc.ncbi.nlm.nih.gov/articles/PMC8227791/
- pmc.ncbi.nlm.nih.gov/articles/PMC11546785/
- pmc.ncbi.nlm.nih.gov/articles/PMC7795577/
Background is reproduced from Peptides Calculator with attribution. The source describes compound-level research. It does not evaluate the identity, quality or suitability of a listed supplier’s product or batch.